Research workbench

Crystal structure of human dual specificity phosphatase 14

Analyse Crystal structure of human dual specificity phosphatase 14 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2WGP
Type: protein
Length: 335 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dual specificity protein phosphatase 14
EC: 3.1.3.48, 3.1.3.16
UniProt: O95147
Ligands: PO4

Structure

x-ray diffraction · 2 distinct chains · 44% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dual specificity protein phosphatase 14 (EC 3.1.3.48, 3.1.3.16)	protein	168	44% helix, 17% strand	O95147
B	Dual specificity protein phosphatase 14 (EC 3.1.3.48, 3.1.3.16)	protein	167	44% helix, 17% strand	O95147

Ligands and binding sites

PO4 · Phosphate ion · ion · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

A–B · 123 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

2WGP · Crystal structure of human dual specificity phosphatase 14 · the same entry in another collection · chain A against A, TM-score 1.00
O95147 · AlphaFold monomer V2.0 prediction for dual specificity protein phosphatase 14 (O95147) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O95147
Elsewhere: RCSB PDB 2WGP · PDBe 2WGP · UniProt O95147

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.