Research workbench
N512P mutant of the DNA binding domain of the adenovirus 5 ssdna binding protein
Analyse N512P mutant of the DNA binding domain of the adenovirus 5 ssdna binding protein in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2WAZ
- Type
- protein
- Length
- 315 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- E2A DNA-binding protein
- UniProt
- Q2KS06
- Ligands
- ZN
- Pockets
- 4 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| X | E2A DNA-binding protein | protein | 315 | 33% helix, 15% strand | Q2KS06 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains X
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 387 | 0.60 | 0.76 | 49 | empty |
| 2 | 152 | 0.51 | 0.79 | 16 | empty |
| 3 | 106 | 0.38 | 0.75 | 17 | empty |
| 4 | 55 | 0.29 | 0.75 | 15 | empty |
Compared structures
- 2WAZ · N512P mutant of the DNA binding domain of the Adenovirus 5 ssDNA binding protein · the same entry in another collection · chain X against X, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q2KS06
- Elsewhere: RCSB PDB 2WAZ · PDBe 2WAZ · UniProt Q2KS06
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