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Structure of the PDZ domain of TAX1 (human T-cell leukemia virus type I) binding protein 3

Analyse Structure of the PDZ domain of TAX1 (human T-cell leukemia virus type I)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2VZ5
Type: protein
Length: 111 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: TAX1-binding protein 3
UniProt: O14907
Ligands: ZN, CL
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	TAX1-binding protein 3	protein	111	14% helix, 36% strand	O14907

Ligands and binding sites

ZN · Zinc ion · metal · 2 copies · chains A
CL · Chloride ion · ion · chains A
IMD · Imidazole · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	56	0.32	0.76	12	empty

Compared structures

2VZ5 · Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3 · the same entry in another collection · chain A against A, TM-score 1.00
O14907 · AlphaFold monomer V2.0 prediction for TAX1-binding protein 3 (O14907) · a predicted model of the same protein · chain A against A, TM-score 0.91

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O14907
Elsewhere: RCSB PDB 2VZ5 · PDBe 2VZ5 · UniProt O14907

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