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Crystal structure of pilw, widely conserved type IV pilus biogenesis factor

Analyse Crystal structure of pilw, widely conserved type IV pilus biogenesis factor in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2VQ2
Type
protein
Length
220 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Putative fimbrial biogenesis and twitching motility protein
UniProt
Q9JZ41
Ligands
MG, CL, SO4, SO3
Pockets
1 · best druggability 0.28

Structure

x-ray diffraction · 1 distinct chain · 78% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APutative fimbrial biogenesis and twitching motility proteinprotein22078% helix, 0% strandQ9JZ41

Ligands and binding sites

  • MG · Magnesium ion · metal · chains A
  • CL · Chloride ion · ion · 3 copies · chains A
  • SO4 · Sulfate ion · ion · chains A
  • SO3 · Sulfite ion · ion · chains A
  • GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1530.280.7412empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

  • 2VQ2 · Crystal structure of PilW, widely conserved type IV pilus biogenesis factor · the same entry in another collection · chain A against A, TM-score 1.00

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