Research workbench
Structure of a loop C-sheet serpin polymer
Analyse Structure of a loop C-sheet serpin polymer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2VH4
- Type
- protein
- Length
- 754 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Tengpin
- UniProt
- Q8R9P5
- Pockets
- 8 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 29% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Tengpin | protein | 380 | 29% helix, 37% strand | Q8R9P5 |
| B | Tengpin | protein | 374 | 28% helix, 36% strand | Q8R9P5 |
Pockets
8 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 759 | 0.70 | 0.76 | 62 | empty |
| 2 | 150 | 0.48 | 0.77 | 20 | empty |
| 3 | 67 | 0.48 | 0.83 | 22 | empty |
| 4 | 129 | 0.39 | 0.74 | 24 | empty |
| 5 | 53 | 0.33 | 0.78 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 261 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 2VH4 · Structure of a loop C-sheet serpin polymer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R9P5
- Elsewhere: RCSB PDB 2VH4 · PDBe 2VH4 · UniProt Q8R9P5
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