Mouse profilin iia in complex with the proline-rich domain of vasp

Structure

x-ray diffraction · 2 distinct chains · 28% helix, 29% strand (DSSP).

Ligands and binding sites

• NA · Sodium ion · metal · chains A
• SO4 · Sulfate ion · ion · 3 copies · chains A
• IPA · Isopropyl alcohol · additive · 2 copies · chains A
• GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–C · 531 Ų buried · 7 hydrogen bonds · protein-protein

Compared structures

• 2V8C · Mouse Profilin IIa in complex with the proline-rich domain of VASP · the same entry in another collection · chain A against A, TM-score 1.00
• P70460 · AlphaFold monomer V2.0 prediction for vasodilator-stimulated phosphoprotein (P70460) · a predicted model of the same protein · chain C against A, TM-score 0.35

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q3V171
• Every structure of UniProt P70460
• Elsewhere: RCSB PDB 2V8C · PDBe 2V8C · UniProt Q3V171 · UniProt P70460