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Crystal structure of ERBB3 binding protein 1 (EBP1)

Analyse Crystal structure of ERBB3 binding protein 1 (EBP1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2V6C
Type: protein
Length: 353 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Proliferation-associated protein 2G4
UniProt: P50580
Pockets: 2 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferation-associated protein 2G4	protein	353	33% helix, 25% strand	P50580

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	231	0.63	0.81	25	empty
2	94	0.39	0.76	20	empty

Compared structures

2V6C · Crystal structure of ErbB3 binding protein 1 (Ebp1) · the same entry in another collection · chain A against A, TM-score 1.00
P50580 · AlphaFold monomer V2.0 prediction for proliferation-associated protein 2G4 (P50580) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P50580
Elsewhere: RCSB PDB 2V6C · PDBe 2V6C · UniProt P50580

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