Research workbench
Apo ldh from the psychrophile C. gunnari
Analyse Apo ldh from the psychrophile C. gunnari in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2V65
- Type
- protein
- Length
- 651 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-lactate dehydrogenase a chain
- EC
- 1.1.1.27
- UniProt
- O93541
- Pockets
- 6 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 46% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-lactate dehydrogenase a chain (EC 1.1.1.27) | protein | 326 | 45% helix, 17% strand | O93541 |
| B | L-lactate dehydrogenase a chain (EC 1.1.1.27) | protein | 325 | 46% helix, 18% strand | O93541 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1076 | 0.75 | 0.78 | 92 | empty |
| 2 | 455 | 0.64 | 0.77 | 43 | empty |
| 3 | 127 | 0.41 | 0.75 | 19 | empty |
| 4 | 115 | 0.41 | 0.76 | 18 | empty |
| 5 | 65 | 0.33 | 0.76 | 19 | empty |
Interfaces
1 interface between chains.
- A–B · 451 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O93541
- Elsewhere: RCSB PDB 2V65 · PDBe 2V65 · UniProt O93541
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.