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Solution structure of rat P2X4 receptor head domain

Analyse Solution structure of rat P2X4 receptor head domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RUP
Type: protein
Length: 58 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: P2X purinoceptor 4
UniProt: P51577
Pockets: 1 · best druggability 0.46

Structure

solution nmr · 1 distinct chain · 0% helix, 31% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	P2X purinoceptor 4	protein	58	0% helix, 31% strand	P51577

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.46	0.81	23	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

2RUP · Solution structure of rat P2X4 receptor head domain · the same entry in another collection · chain A against A, TM-score 1.00
P51577 · AlphaFold monomer V2.0 prediction for P2X purinoceptor 4 (P51577) · a predicted model of the same protein · chain A against A, TM-score 0.65

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P51577
Elsewhere: RCSB PDB 2RUP · PDBe 2RUP · UniProt P51577

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