Research workbench
Complex structure of the zf-cw domain and the H3K4ME3 peptide
Analyse Complex structure of the zf-cw domain and the H3K4ME3 peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2RR4
- Type
- protein
- Length
- 79 residues
- Chains
- 2
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Zinc finger cw-type pwwp domain protein 1; Histone H3
- UniProt
- Q9H0M4, A8K4Y7
- Ligands
- ZN
Structure
solution nmr · 2 distinct chains · 8% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Zinc finger cw-type pwwp domain protein 1 | protein | 69 | 9% helix, 17% strand | Q9H0M4 |
| B | Histone H3 | protein | 10 | 0% helix, 50% strand | A8K4Y7 |
Ligands and binding sites
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 679 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 1 modified (methylation).
Compared structures
- 2RR4 · Complex structure of the zf-CW domain and the H3K4me3 peptide · the same entry in another collection · chain A against A, TM-score 1.00
- Q9H0M4 · AlphaFold monomer V2.0 prediction for zinc finger cw-type pwwp domain protein 1 (Q9H0M4) · a predicted model of the same protein · chain A against A, TM-score 0.70
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9H0M4
- Every structure of UniProt A8K4Y7
- Elsewhere: RCSB PDB 2RR4 · PDBe 2RR4 · UniProt Q9H0M4 · UniProt A8K4Y7
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