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Solution structure of juvenile hormone binding protein from silkworm in complex with jh III

Analyse Solution structure of juvenile hormone binding protein from silkworm in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RQF
Type: protein
Length: 227 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hemolymph juvenile hormone binding protein
UniProt: Q9U556
Ligands: JH3
Pockets: 1 · best druggability 0.85

Structure

solution nmr · 1 distinct chain · 24% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hemolymph juvenile hormone binding protein	protein	227	24% helix, 40% strand	Q9U556

Ligands and binding sites

JH3 · methyl (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	289	0.85	0.95	42	JH3

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

2RQF · Solution structure of juvenile hormone binding protein from silkworm in complex with JH… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9U556
Elsewhere: RCSB PDB 2RQF · PDBe 2RQF · UniProt Q9U556

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