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Solution structure of the at-rich interaction domain (arid) of JUMONJI/JARID2

Analyse Solution structure of the at-rich interaction domain (arid) of JUMONJI/JARID2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2RQ5
Type
protein
Length
121 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Protein jumonji
UniProt
Q62315
Pockets
1 · best druggability 0.51

Structure

solution nmr · 1 distinct chain · 58% helix, 3% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AProtein jumonjiprotein12158% helix, 3% strandQ62315

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.510.8616empty

Compared structures

  • 2RQ5 · Solution structure of the AT-rich interaction domain (ARID) of Jumonji/JARID2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q62315 · AlphaFold monomer V2.0 prediction for protein jumonji (Q62315) · a predicted model of the same protein · chain A against A, TM-score 0.74

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