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Solution structure of the N-terminal sap domain of sumo E3 ligases from saccharomyces cerevisiae

Analyse Solution structure of the N-terminal sap domain of sumo E3 ligases from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RNN
Type: protein
Length: 114 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: E3 sumo-protein ligase SIZ1
EC: 6.-.-.-
UniProt: Q04195
Pockets: 1 · best druggability 0.37

Structure

solution nmr · 1 distinct chain · 59% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	E3 sumo-protein ligase SIZ1 (EC 6.-.-.-)	protein	114	59% helix, 0% strand	Q04195

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	95	0.37	0.75	24	empty

Compared structures

2RNN · Solution Structure of the N-terminal SAP Domain of SUMO E3 Ligases from Saccharomyces… · the same entry in another collection · chain A against A, TM-score 1.00
Q04195 · AlphaFold monomer V2.0 prediction for E3 sumo-protein ligase SIZ1 (Q04195) · a predicted model of the same protein · chain A against A, TM-score 0.72

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q04195
Elsewhere: RCSB PDB 2RNN · PDBe 2RNN · UniProt Q04195

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