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Tetracenomycin ARO/CYC mutant R69A

Analyse Tetracenomycin ARO/CYC mutant R69A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RES
Type: protein
Length: 152 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmn
UniProt: P16559
Pockets: 1 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 32% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Multifunctional cyclase-dehydratase-3-O-methyl transferase tcmn	protein	152	32% helix, 43% strand	P16559

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	400	0.76	0.85	48	empty

Compared structures

2RES · Tetracenomycin ARO/CYC mutant R69A · the same entry in another collection · chain A against A, TM-score 1.00
P16559 · AlphaFold monomer V2.0 prediction for multifunctional cyclase- dehydratase-3-O-methyl… · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P16559
Elsewhere: RCSB PDB 2RES · PDBe 2RES · UniProt P16559

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