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Crystal structure of human sulfotransferase 1C3 (SULT1C3) in complex with pap

Analyse Crystal structure of human sulfotransferase 1C3 (SULT1C3) in complex with pap in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2REO
Type: protein
Length: 222 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative sulfotransferase 1C3
EC: 2.8.2.-
UniProt: Q6IMI6
Ligands: A3P
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative sulfotransferase 1C3 (EC 2.8.2.-)	protein	222	48% helix, 10% strand	Q6IMI6

Ligands and binding sites

A3P · Adenosine-3'-5'-diphosphate · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	237	0.74	0.88	34	A3P

Compared structures

2REO · Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP · the same entry in another collection · chain A against A, TM-score 1.00
Q6IMI6 · AlphaFold monomer V2.0 prediction for sulfotransferase 1C3 (Q6IMI6) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6IMI6
Elsewhere: RCSB PDB 2REO · PDBe 2REO · UniProt Q6IMI6

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