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N-methylbenzylamine in complex with cytochrome C peroxidase W191G

Analyse N-methylbenzylamine in complex with cytochrome C peroxidase W191G in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2RBT
Type: protein
Length: 292 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytochrome C peroxidase
EC: 1.11.1.5
UniProt: A7A026
Ligands: HEM, 271, PO4
Pockets: 2 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 8% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
X	Cytochrome C peroxidase (EC 1.11.1.5)	protein	292	50% helix, 8% strand	A7A026

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains X
271 · N-methyl-1-phenylmethanamine · ligand · chains X
PO4 · Phosphate ion · ion · chains X
MPD · (4S)-2-methyl-2,4-pentanediol · additive · 2 copies · chains X

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	378	0.81	0.90	52	PO4, HEM, 271
2	89	0.39	0.77	20	MPD

Compared structures

2RBT · n-methylbenzylamine in complex with Cytochrome C Peroxidase W191G · the same entry in another collection · chain X against X, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A7A026
Elsewhere: RCSB PDB 2RBT · PDBe 2RBT · UniProt A7A026

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