Research workbench

Delta-R306 deacetoxycephalosporin C synthase complexed with iron and 2-oxoglutarate.

Analyse Delta-R306 deacetoxycephalosporin C synthase complexed with iron and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1E5I
Type: protein
Length: 264 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Deacetoxycephalosporin C synthase
EC: 1.14.20.1
UniProt: P18548
Ligands: AKG, FE2
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Deacetoxycephalosporin C synthase (EC 1.14.20.1)	protein	264	33% helix, 26% strand	P18548

Ligands and binding sites

AKG · 2-oxoglutaric acid · ligand · chains A
FE2 · Fe (II) ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	74	0.63	0.91	21	FE2, AKG

Compared structures

1E5I · Delta-R306 deacetoxycephalosporin C synthase complexed with iron and 2-oxoglutarate. · the same entry in another collection · chain A against A, TM-score 1.00
P18548 · AlphaFold monomer V2.0 prediction for deacetoxycephalosporin C synthase (P18548) · a predicted model of the same protein · chain A against A, TM-score 0.91

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P18548
Elsewhere: RCSB PDB 1E5I · PDBe 1E5I · UniProt P18548

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.