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Crystal structure of the long-chain fatty acid transporter fadl mutant delta N3

Analyse Crystal structure of the long-chain fatty acid transporter fadl mutant delta N3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2R89
Type: protein
Length: 726 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Long-chain fatty acid transport protein
UniProt: P10384
Pockets: 4 · best druggability 0.86

Structure

x-ray diffraction · 1 distinct chain · 9% helix, 57% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Long-chain fatty acid transport protein	protein	363	9% helix, 57% strand	P10384

Pockets

4 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1188	0.86	0.86	105	empty
2	844	0.82	0.84	77	empty
3	383	0.62	0.78	37	empty
4	336	0.59	0.77	35	empty

Interfaces

1 interface between chains.

A–B · 638 Å² buried · 4 hydrogen bonds · protein-protein

Compared structures

2R89 · Crystal structure of the long-chain fatty acid transporter FadL mutant delta N3 · the same entry in another collection · chain A against A, TM-score 1.00
P10384 · AlphaFold monomer V2.0 prediction for long-chain fatty acid transport protein (P10384) · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10384
Elsewhere: RCSB PDB 2R89 · PDBe 2R89 · UniProt P10384

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