Research workbench
Crystal structure of FMN-binding protein (NP_142786.1) from pyrococcus horikoshii at 1.35 a resolution
Analyse Crystal structure of FMN-binding protein (NP_142786.1) from pyrococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2R6V
- Type
- protein
- Length
- 182 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein PH0856
- UniProt
- O58586
- Ligands
- FMN, NCA
- Pockets
- 2 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 22% helix, 37% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein PH0856 | protein | 182 | 22% helix, 37% strand | O58586 |
Ligands and binding sites
- FMN · Flavin mononucleotide · ligand · chains A
- NCA · Nicotinamide · ligand · chains A
- EDO · 1,2-ethanediol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 360 | 0.74 | 0.85 | 35 | FMN, NCA |
| 2 | 156 | 0.45 | 0.75 | 20 | empty |
Modifications
Observed in the structure: 4 modified (engineered).
Compared structures
- 2R6V · Crystal structure of FMN-binding protein (NP_142786.1) from Pyrococcus horikoshii at 1.35… · the same entry in another collection · chain A against A, TM-score 1.00
- O58586 · AlphaFold monomer V2.0 prediction for uncharacterized protein PH0856 (O58586) · a predicted model of the same protein · chain A against A, TM-score 0.94
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O58586
- Elsewhere: RCSB PDB 2R6V · PDBe 2R6V · UniProt O58586
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.