Research workbench

Draft crystal structure of the vault shell at 9 ångströms resolution

Analyse Draft crystal structure of the vault shell at 9 ångströms resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QZV
Type: protein
Length: 1,498 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major vault protein
UniProt: Q62667
Pockets: 18 · best druggability 0.71

Structure

x-ray diffraction · 1 distinct chain · 27% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Major vault protein	protein	749	27% helix, 15% strand	Q62667

Pockets

18 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	573	0.71	0.80	80	empty
2	680	0.63	0.74	85	empty
3	426	0.63	0.77	51	empty
4	567	0.61	0.74	85	empty
5	246	0.52	0.76	38	empty

Interfaces

1 interface between chains.

A–B · 2938 Å² buried · 12 hydrogen bonds · protein-protein

Compared structures

2QZV · Draft Crystal Structure of the Vault Shell at 9 Angstroms Resolution · the same entry in another collection · chain A against A, TM-score 1.00
Q62667 · AlphaFold monomer V2.0 prediction for major vault protein (Q62667) · a predicted model of the same protein · chain A against A, TM-score 0.37

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q62667
Elsewhere: RCSB PDB 2QZV · PDBe 2QZV · UniProt Q62667

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.