Research workbench
Crystal structure of a putative tena-like thiaminase (tena-1, SSO2206) from sulfolobus solfataricus P2 at 1.50 a resolution
Analyse Crystal structure of a putative tena-like thiaminase (tena-1, SSO2206) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2QZC
- Type
- protein
- Length
- 413 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional activator tena-1
- UniProt
- Q97WL0
- Pockets
- 2 · best druggability 0.70
Structure
x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional activator tena-1 | protein | 209 | 78% helix, 0% strand | Q97WL0 |
| B | Transcriptional activator tena-1 | protein | 204 | 76% helix, 0% strand | Q97WL0 |
Ligands and binding sites
- GOL · Glycerol · additive · 7 copies · chains A, B
- IMD · Imidazole · additive · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 421 | 0.70 | 0.81 | 40 | IMD, GOL |
| 2 | 364 | 0.67 | 0.80 | 31 | IMD, GOL |
Interfaces
1 interface between chains.
- A–B · 759 Ų buried · 10 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 2QZC · Crystal structure of a putative tena-like thiaminase (tena-1, sso2206) from sulfolobus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97WL0
- Elsewhere: RCSB PDB 2QZC · PDBe 2QZC · UniProt Q97WL0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.