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First crystal structure of a psychrophile class C beta- lactamase

Analyse First crystal structure of a psychrophile class C beta- lactamase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QZ6
Type: protein
Length: 349 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Beta-lactamase
EC: 3.5.2.6
UniProt: P85302
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-lactamase (EC 3.5.2.6)	protein	349	40% helix, 22% strand	P85302

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	209	0.53	0.78	29	empty
2	117	0.42	0.76	25	empty

Compared structures

2QZ6 · First crystal structure of a psychrophile class C beta-lactamase · the same entry in another collection · chain A against A, TM-score 1.00
P85302 · AlphaFold monomer V2.0 prediction for beta-lactamase (P85302) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P85302
Elsewhere: RCSB PDB 2QZ6 · PDBe 2QZ6 · UniProt P85302

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