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Crystal structure of the C-terminal domain of aida

Analyse Crystal structure of the C-terminal domain of aida in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QZ5
Type: protein
Length: 306 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Axin interactor, dorsalization associated protein
UniProt: Q8C4Q6
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 6% helix, 47% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Axin interactor, dorsalization associated protein	protein	152	6% helix, 47% strand	Q8C4Q6
B	Axin interactor, dorsalization associated protein	protein	154	6% helix, 46% strand	Q8C4Q6

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	329	0.57	0.76	42	empty

Interfaces

1 interface between chains.

A–B · 181 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

2QZ5 · Crystal Structure of the C-terminal domain of Aida · the same entry in another collection · chain A against A, TM-score 1.00
Q8C4Q6 · AlphaFold monomer V2.0 prediction for axin interactor, dorsalization- associated protein… · a predicted model of the same protein · chain B against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8C4Q6
Elsewhere: RCSB PDB 2QZ5 · PDBe 2QZ5 · UniProt Q8C4Q6

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