Research workbench

Crystal structure of an uncharacterized conserved protein from methanopyrus kandleri

Analyse Crystal structure of an uncharacterized conserved protein from methanopyrus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2QYA
Type: protein
Length: 460 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized conserved protein
UniProt: Q8TWR4
Pockets: 6 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 26% helix, 37% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	Uncharacterized conserved protein	protein	115	26% helix, 37% strand	Q8TWR4

Pockets

6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	361	0.56	0.75	36	empty
2	358	0.55	0.74	40	empty
3	184	0.50	0.77	25	empty
4	147	0.50	0.79	23	empty
5	147	0.45	0.76	21	empty

Interfaces

4 interfaces between chains.

C–D · 1359 Å² buried · 18 hydrogen bonds · protein-protein
A–B · 1315 Å² buried · 19 hydrogen bonds · protein-protein
A–D · 271 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 262 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

2QYA · Crystal structure of an uncharacterized conserved protein from Methanopyrus kandleri · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8TWR4
Elsewhere: RCSB PDB 2QYA · PDBe 2QYA · UniProt Q8TWR4

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.