Research workbench
Structure of the minor pseudopilin epsh from the type 2 secretion system of vibrio cholerae
Analyse Structure of the minor pseudopilin epsh from the type 2 secretion system of… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2QV8
- Type
- protein
- Length
- 268 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- General secretion pathway protein H
- UniProt
- P45774
- Pockets
- 3 · best druggability 0.61
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | General secretion pathway protein H | protein | 144 | 16% helix, 33% strand | P45774 |
| B | General secretion pathway protein H | protein | 124 | 21% helix, 38% strand | P45774 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 285 | 0.61 | 0.79 | 40 | empty |
| 2 | 144 | 0.41 | 0.74 | 17 | empty |
| 3 | 50 | 0.25 | 0.73 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 473 Ų buried · 1 hydrogen bond · protein-protein
Modifications
Observed in the structure: 2 modified (engineered).
Compared structures
- 2QV8 · Structure of the minor pseudopilin EpsH from the Type 2 Secretion System of Vibrio… · the same entry in another collection · chain A against A, TM-score 1.00
- P45774 · AlphaFold monomer V2.0 prediction for type II secretion system protein H (P45774) · a predicted model of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P45774
- Elsewhere: RCSB PDB 2QV8 · PDBe 2QV8 · UniProt P45774
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