Green fluorescent protein: cyclized-only intermediate of chromophore maturation in the Q183E variant

Structure

x-ray diffraction · 1 distinct chain · 12% helix, 52% strand (DSSP).

Ligands and binding sites

• CZO · [(2R,4S)-2-[(1S,2R)-1-amino-2-hydroxypropyl]-2-hydroxy-4-(4-hydroxybenzyl)-5-oxoimidazolidin-1-yl]acetic acid · ligand · chains A
• MG · Magnesium ion · metal · chains A
• EDO · 1,2-ethanediol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 2 covalent (covalent ligand).

Compared structures

• 2QRF · Green Fluorescent Protein: Cyclized-only Intermediate of Chromophore Maturation in the… · the same entry in another collection · chain A against A, TM-score 1.00
• P42212 · AlphaFold monomer V2.0 prediction for green fluorescent protein (P42212) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P42212
• Elsewhere: RCSB PDB 2QRF · PDBe 2QRF · UniProt P42212