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High resolution structure of peroxisone proliferation-activated receptor gamma and characterisation of its interaction with the co- activator transcriptional intermediary factor 2
Analyse High resolution structure of peroxisone proliferation-activated receptor gamma… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2QMV
- Type
- protein
- Length
- 270 residues
- Chains
- 1
- Method
- solution nmr
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Peroxisome proliferator-activated receptor gamma
- UniProt
- P37231
- Pockets
- 3 · best druggability 0.69
Structure
solution nmr · 1 distinct chain · 63% helix, 4% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Peroxisome proliferator-activated receptor gamma | protein | 270 | 63% helix, 4% strand | P37231 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 184 | 0.69 | 0.86 | 41 | empty |
| 2 | 229 | 0.58 | 0.79 | 29 | empty |
| 3 | 63 | 0.42 | 0.81 | 18 | empty |
Compared structures
- 2QMV · High Resolution Structure of Peroxisone Proliferation-Activated Receptor gamma and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P37231
- Elsewhere: RCSB PDB 2QMV · PDBe 2QMV · UniProt P37231
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