Research workbench
Structural basis for activation of plant immunity by bacterial effector protein avrpto
Analyse Structural basis for activation of plant immunity by bacterial effector protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2QKW
- Type
- protein
- Length
- 393 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Avirulence protein; Protein kinase
- EC
- 2.7.11.1
- UniProt
- Q08242, Q40234
- Pockets
- 5 · best druggability 0.75
Structure
x-ray diffraction · 2 distinct chains · 43% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Avirulence protein | protein | 101 | 70% helix, 3% strand | Q08242 |
| B | Protein kinase (EC 2.7.11.1) | protein | 292 | 34% helix, 13% strand | Q40234 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 645 | 0.75 | 0.81 | 62 | empty |
| 2 | 97 | 0.56 | 0.85 | 19 | empty |
| 3 | 66 | 0.39 | 0.79 | 13 | empty |
| 4 | 114 | 0.38 | 0.74 | 22 | empty |
| 5 | 56 | 0.27 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 755 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 modified (phosphorylation).
Compared structures
- 2QKW · Structural basis for activation of plant immunity by bacterial effector protein AvrPto · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q08242
- Every structure of UniProt Q40234
- Elsewhere: RCSB PDB 2QKW · PDBe 2QKW · UniProt Q08242 · UniProt Q40234
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.