Research workbench
Crystal structure of novel immune-type receptor 10 extracellular fragment from ictalurus punctatus
Analyse Crystal structure of novel immune-type receptor 10 extracellular fragment from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2QHL
- Type
- protein
- Length
- 550 residues
- Chains
- 5
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Novel immune-type receptor 10
- UniProt
- Q8UWK5
- Pockets
- 9 · best druggability 0.46
Structure
x-ray diffraction · 3 distinct chains · 6% helix, 51% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, E | Novel immune-type receptor 10 | protein | 110 | 5% helix, 51% strand | Q8UWK5 |
| C | Novel immune-type receptor 10 | protein | 111 | 5% helix, 50% strand | Q8UWK5 |
| D | Novel immune-type receptor 10 | protein | 109 | 8% helix, 52% strand | Q8UWK5 |
Pockets
9 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 134 | 0.46 | 0.78 | 18 | empty |
| 2 | 132 | 0.42 | 0.75 | 23 | empty |
| 3 | 101 | 0.42 | 0.77 | 22 | empty |
| 4 | 93 | 0.42 | 0.78 | 22 | empty |
| 5 | 110 | 0.40 | 0.75 | 19 | empty |
Interfaces
4 interfaces between chains.
- C–E · 1321 Ų buried · 18 hydrogen bonds · protein-protein
- A–D · 1318 Ų buried · 17 hydrogen bonds · protein-protein
- B–C · 689 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 454 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 disulfide (disulfide).
Compared structures
- 2QHL · Crystal Structure of Novel Immune-Type Receptor 10 Extracellular Fragment from Ictalurus… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8UWK5
- Elsewhere: RCSB PDB 2QHL · PDBe 2QHL · UniProt Q8UWK5
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