Research workbench
Enzyme iia from the lactose specific pts from lactococcus lactis
Analyse Enzyme iia from the lactose specific pts from lactococcus lactis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1E2A
- Type
- protein
- Length
- 306 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Enzyme iia
- EC
- 2.7.1.69
- UniProt
- P23532
- Ligands
- MG
- Pockets
- 1 · best druggability 0.75
Structure
x-ray diffraction · 1 distinct chain · 85% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Enzyme iia (EC 2.7.1.69) | protein | 102 | 85% helix, 0% strand | P23532 |
Ligands and binding sites
- MG · Magnesium ion · metal · chains A, B, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.75 | 0.98 | 12 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1136 Ų buried · 14 hydrogen bonds · protein-protein
- A–C · 1111 Ų buried · 9 hydrogen bonds · protein-protein
- A–B · 1108 Ų buried · 12 hydrogen bonds · protein-protein
Compared structures
- 1E2A · Enzyme iia from the lactose specific pts from lactococcus lactis · the same entry in another collection · chain C against C, TM-score 1.00
- P23532 · AlphaFold monomer V2.0 prediction for pts system lactose-specific eiia component (P23532) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P23532
- Elsewhere: RCSB PDB 1E2A · PDBe 1E2A · UniProt P23532
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