Research workbench
Ensemble refinement of the crystal structure of uncharacterized protein LOC79017 from homo sapiens
Analyse Ensemble refinement of the crystal structure of uncharacterized protein… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Q53
- Type
- protein
- Length
- 338 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein C7ORF24
- UniProt
- O75223
- Pockets
- 7 · best druggability 0.63
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein C7ORF24 | protein | 169 | 29% helix, 37% strand | O75223 |
| B | Uncharacterized protein C7ORF24 | protein | 169 | 27% helix, 38% strand | O75223 |
Pockets
7 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 234 | 0.63 | 0.82 | 31 | empty |
| 2 | 242 | 0.62 | 0.81 | 32 | empty |
| 3 | 136 | 0.56 | 0.82 | 23 | empty |
| 4 | 160 | 0.53 | 0.80 | 23 | empty |
| 5 | 236 | 0.52 | 0.76 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 886 Ų buried · 24 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 2Q53 · Ensemble refinement of the crystal structure of uncharacterized protein loc79017 from… · the same entry in another collection · chain A against A, TM-score 1.00
- O75223 · AlphaFold monomer V2.0 prediction for gamma-glutamylcyclotransferase (O75223) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O75223
- Elsewhere: RCSB PDB 2Q53 · PDBe 2Q53 · UniProt O75223
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.