Research workbench
Crystal structure of rhesus macaque CD8 alpha-alpha homodimer
Analyse Crystal structure of rhesus macaque CD8 alpha-alpha homodimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Q3A
- Type
- protein
- Length
- 231 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- CD8
- Pockets
- 3 · best druggability 0.49
Structure
x-ray diffraction · 2 distinct chains · 3% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | CD8 | protein | 117 | 3% helix, 46% strand | — |
| B | CD8 | protein | 114 | 3% helix, 46% strand | — |
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 89 | 0.49 | 0.82 | 21 | empty |
| 2 | 128 | 0.39 | 0.74 | 24 | empty |
| 3 | 94 | 0.35 | 0.74 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 1170 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2Q3A · Crystal Structure of Rhesus Macaque CD8 Alpha-Alpha Homodimer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2Q3A · PDBe 2Q3A
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