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Crystal structure of the Y82F variant of ECH2 decarboxylase domain of curf from lyngbya majuscula
Analyse Crystal structure of the Y82F variant of ECH2 decarboxylase domain of curf from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Q35
- Type
- protein
- Length
- 243 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Curf
- UniProt
- Q6DNE7
- Ligands
- CL
- Pockets
- 4 · best druggability 0.74
Structure
x-ray diffraction · 1 distinct chain · 51% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Curf | protein | 243 | 51% helix, 18% strand | Q6DNE7 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 110 | 0.74 | 0.94 | 29 | GOL |
| 2 | 242 | 0.55 | 0.77 | 28 | empty |
| 3 | 103 | 0.39 | 0.75 | 18 | empty |
| 4 | 69 | 0.30 | 0.74 | 18 | empty |
Compared structures
- 2Q35 · Crystal Structure of the Y82F variant of ECH2 decarboxylase domain of CurF from Lyngbya… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6DNE7
- Elsewhere: RCSB PDB 2Q35 · PDBe 2Q35 · UniProt Q6DNE7
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