Research workbench
Ancestral corticoid receptor in complex with cortisol
Analyse Ancestral corticoid receptor in complex with cortisol in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2Q1V
- Type
- protein
- Length
- 244 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Anccr
- Ligands
- PDN
- Pockets
- 4 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 69% helix, 5% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Anccr | protein | 244 | 69% helix, 5% strand | — |
Ligands and binding sites
- PDN · 17,21-dihydroxypregna-1,4-diene-3,11,20-trione · ligand · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 193 | 0.84 | 0.98 | 24 | PDN |
| 2 | 154 | 0.64 | 0.86 | 23 | empty |
| 3 | 122 | 0.48 | 0.79 | 22 | empty |
| 4 | 72 | 0.31 | 0.73 | 13 | empty |
Compared structures
- 2Q1V · Ancestral corticoid receptor in complex with cortisol · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2Q1V · PDBe 2Q1V
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