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Crystal structure of staphylococcal nuclease variant V66N/P117G/H124L/S128A at room temperature

Analyse Crystal structure of staphylococcal nuclease variant V66N/P117G/H124L/S128A at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2PZW
Type: protein
Length: 130 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thermonuclease
EC: 3.1.31.1
UniProt: Q8NXI6
Pockets: 1 · best druggability 0.41

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thermonuclease (EC 3.1.31.1)	protein	130	28% helix, 33% strand	Q8NXI6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	77	0.41	0.79	16	empty

Compared structures

2PZW · Crystal structure of Staphylococcal nuclease variant V66N/P117G/H124L/S128A at room… · the same entry in another collection · chain A against A, TM-score 1.00
Q8NXI6 · AlphaFold monomer V2.0 prediction for thermonuclease (Q8NXI6) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NXI6
Elsewhere: RCSB PDB 2PZW · PDBe 2PZW · UniProt Q8NXI6

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