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Crystal structure of staphylococcal nuclease variant V66Q/P117G/H124L/S128A at 100 K

Analyse Crystal structure of staphylococcal nuclease variant V66Q/P117G/H124L/S128A at… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2PZT
Type: protein
Length: 130 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thermonuclease
EC: 3.1.31.1
UniProt: Q8NXI6
Ligands: PO4
Pockets: 1 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 28% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thermonuclease (EC 3.1.31.1)	protein	130	28% helix, 33% strand	Q8NXI6

Ligands and binding sites

PO4 · Phosphate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.40	0.79	16	empty

Compared structures

2PZT · Crystal structure of Staphylococcal nuclease variant V66Q/P117G/H124L/S128A at 100 K · the same entry in another collection · chain A against A, TM-score 1.00
Q8NXI6 · AlphaFold monomer V2.0 prediction for thermonuclease (Q8NXI6) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8NXI6
Elsewhere: RCSB PDB 2PZT · PDBe 2PZT · UniProt Q8NXI6

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