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Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor PRP8

Analyse Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P87
Type: protein
Length: 246 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pre-mRNA-splicing factor PRP8
UniProt: P34369
Pockets: 1 · best druggability 0.45

Structure

x-ray diffraction · 1 distinct chain · 23% helix, 29% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pre-mRNA-splicing factor PRP8	protein	246	23% helix, 29% strand	P34369

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	115	0.45	0.78	24	empty

Compared structures

2P87 · Crystal structure of the C-terminal domain of C. elegans pre-mRNA splicing factor Prp8 · the same entry in another collection · chain A against A, TM-score 1.00
P34369 · AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor 8 homolog (P34369) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P34369
Elsewhere: RCSB PDB 2P87 · PDBe 2P87 · UniProt P34369

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