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Crystal structure of genomically encoded fosfomycin resistance protein, fosx, from listeria monocytogenes (tetragonal form)

Analyse Crystal structure of genomically encoded fosfomycin resistance protein, fosx… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P7O
Type: protein
Length: 253 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glyoxalase family protein
UniProt: Q71YW5
Ligands: MN
Pockets: 1 · best druggability 0.81

Structure

x-ray diffraction · 2 distinct chains · 23% helix, 32% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glyoxalase family protein	protein	127	24% helix, 32% strand	Q71YW5
B	Glyoxalase family protein	protein	126	23% helix, 33% strand	Q71YW5

Ligands and binding sites

MN · Manganese (II) ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	207	0.81	0.94	31	empty

Interfaces

1 interface between chains.

A–B · 1776 Å² buried · 32 hydrogen bonds · protein-protein

Compared structures

2P7O · Crystal structure of genomically encoded fosfomycin resistance protein, FosX, from… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q71YW5
Elsewhere: RCSB PDB 2P7O · PDBe 2P7O · UniProt Q71YW5

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