Research workbench
Crystal structure of AQ_1716 from aquifex aeolicus VF5
Analyse Crystal structure of AQ_1716 from aquifex aeolicus VF5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2P68
- Type
- protein
- Length
- 484 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-oxoacyl-[acyl-carrier-protein] reductase
- EC
- 1.1.1.100
- UniProt
- O67610
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · 2 distinct chains · 51% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) | protein | 248 | 52% helix, 16% strand | O67610 |
| B | 3-oxoacyl-[acyl-carrier-protein] reductase (EC 1.1.1.100) | protein | 236 | 50% helix, 15% strand | O67610 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 567 | 0.71 | 0.79 | 48 | empty |
| 2 | 602 | 0.70 | 0.78 | 47 | empty |
| 3 | 123 | 0.42 | 0.76 | 19 | empty |
| 4 | 57 | 0.41 | 0.81 | 9 | empty |
| 5 | 69 | 0.40 | 0.79 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1639 Ų buried · 18 hydrogen bonds · protein-protein
Compared structures
- 2P68 · Crystal Structure of aq_1716 from Aquifex Aeolicus VF5 · the same entry in another collection · chain A against A, TM-score 1.00
- O67610 · AlphaFold monomer V2.0 prediction for 3-oxoacyl-[acyl-carrier- protein] reductase fabg… · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67610
- Elsewhere: RCSB PDB 2P68 · PDBe 2P68 · UniProt O67610
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.