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Crystal structure of LAO/AO transport system kinase

Analyse Crystal structure of LAO/AO transport system kinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2P67
Type: protein
Length: 302 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LAO/AO transport system kinase
EC: 2.7.-.-
UniProt: P27254
Ligands: NA, CL
Pockets: 2 · best druggability 0.55

Structure

x-ray diffraction · 1 distinct chain · 57% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LAO/AO transport system kinase (EC 2.7.-.-)	protein	302	57% helix, 15% strand	P27254

Ligands and binding sites

NA · Sodium ion · metal · chains A
CL · Chloride ion · ion · 4 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	217	0.55	0.78	35	empty
2	205	0.50	0.76	19	NA

Compared structures

2P67 · Crystal structure of LAO/AO transport system kinase · the same entry in another collection · chain A against A, TM-score 1.00
P27254 · AlphaFold monomer V2.0 prediction for GTPase argk (P27254) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P27254
Elsewhere: RCSB PDB 2P67 · PDBe 2P67 · UniProt P27254

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