Research workbench
A ferredoxin-like metallo-beta-lactamase superfamily protein from thermoanaerobacter tengcongensis
Analyse A ferredoxin-like metallo-beta-lactamase superfamily protein from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2P4Z
- Type
- protein
- Length
- 551 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Metal-dependent hydrolases of the beta-lactamase superfamily II
- UniProt
- Q8R8V2
- Ligands
- FE
- Pockets
- 9 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 30% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Metal-dependent hydrolases of the beta-lactamase superfamily II | protein | 275 | 30% helix, 30% strand | Q8R8V2 |
| B | Metal-dependent hydrolases of the beta-lactamase superfamily II | protein | 276 | 30% helix, 30% strand | Q8R8V2 |
Ligands and binding sites
- FE · Fe (III) ion · metal · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 259 | 0.59 | 0.79 | 25 | FE |
| 2 | 218 | 0.59 | 0.80 | 25 | FE |
| 3 | 106 | 0.47 | 0.80 | 17 | empty |
| 4 | 103 | 0.45 | 0.78 | 17 | empty |
| 5 | 59 | 0.43 | 0.82 | 20 | empty |
Interfaces
1 interface between chains.
- A–B · 1189 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2P4Z · A Ferredoxin-like Metallo-beta-lactamase Superfamily Protein from Thermoanaerobacter… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8R8V2
- Elsewhere: RCSB PDB 2P4Z · PDBe 2P4Z · UniProt Q8R8V2
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.