Research workbench
Crystal structure analysis of the dimeric form of the srcr domain of mouse marco
Analyse Crystal structure analysis of the dimeric form of the srcr domain of mouse marco in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2OYA
- Type
- protein
- Length
- 204 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Macrophage receptor marco
- UniProt
- Q60754
- Ligands
- SO4
- Pockets
- 1 · best druggability 0.41
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Macrophage receptor marco | protein | 102 | 19% helix, 35% strand | Q60754 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 141 | 0.41 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1439 Ų buried · 30 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 2OYA · Crystal structure analysis of the dimeric form of the SRCR domain of mouse MARCO · the same entry in another collection · chain A against A, TM-score 1.00
- Q60754 · AlphaFold monomer V2.0 prediction for macrophage receptor marco (Q60754) · a predicted model of the same protein · chain A against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q60754
- Elsewhere: RCSB PDB 2OYA · PDBe 2OYA · UniProt Q60754
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