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Crystal structure of protein EF1440 from enterococcus faecalis

Analyse Crystal structure of protein EF1440 from enterococcus faecalis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OX7
Type: protein
Length: 574 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein
UniProt: Q835D7
Pockets: 8 · best druggability 0.80

Structure

x-ray diffraction · 2 distinct chains · 6% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Hypothetical protein	protein	144	6% helix, 49% strand	Q835D7
C, D	Hypothetical protein	protein	143	6% helix, 48% strand	Q835D7

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	319	0.80	0.91	53	empty
2	94	0.67	0.91	33	empty
3	85	0.61	0.89	29	empty
4	102	0.36	0.74	21	empty
5	86	0.36	0.75	19	empty

Interfaces

6 interfaces between chains.

B–C · 1990 Å² buried · 23 hydrogen bonds · protein-protein
A–D · 1965 Å² buried · 25 hydrogen bonds · protein-protein
A–B · 430 Å² buried · 5 hydrogen bonds · protein-protein
C–D · 375 Å² buried · 3 hydrogen bonds · protein-protein
B–D · 284 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 16 modified (engineered).

Compared structures

2OX7 · Crystal structure of protein EF1440 from Enterococcus faecalis · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q835D7
Elsewhere: RCSB PDB 2OX7 · PDBe 2OX7 · UniProt Q835D7

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