Research workbench

X-ray structure of human complement protein C8GAMMA Y83W mutant

Analyse X-ray structure of human complement protein C8GAMMA Y83W mutant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OVA
Type: protein
Length: 164 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Complement component 8, gamma polypeptide
UniProt: Q14CU0
Pockets: 1 · best druggability 0.56

Structure

x-ray diffraction · 1 distinct chain · 16% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Complement component 8, gamma polypeptide	protein	164	16% helix, 44% strand	Q14CU0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	243	0.56	0.78	35	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2OVA · X-ray structure of Human Complement Protein C8gamma Y83W Mutant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q14CU0
Elsewhere: RCSB PDB 2OVA · PDBe 2OVA · UniProt Q14CU0

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.