Research workbench
Crystal structure of L-fuculose-1-phosphate aldolase from bacteroides thetaiotaomicron
Analyse Crystal structure of L-fuculose-1-phosphate aldolase from bacteroides… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2OPI
- Type
- protein
- Length
- 412 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- L-fuculose-1-phosphate aldolase
- EC
- 4.1.2.17
- UniProt
- Q9RQ12
- Ligands
- SO4
- Pockets
- 2 · best druggability 0.53
Structure
x-ray diffraction · 2 distinct chains · 40% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | L-fuculose-1-phosphate aldolase (EC 4.1.2.17) | protein | 203 | 40% helix, 18% strand | Q9RQ12 |
| B | L-fuculose-1-phosphate aldolase (EC 4.1.2.17) | protein | 209 | 40% helix, 18% strand | Q9RQ12 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 84 | 0.53 | 0.85 | 25 | SO4 |
| 2 | 229 | 0.51 | 0.76 | 32 | empty |
Interfaces
1 interface between chains.
- A–B · 1234 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 2OPI · Crystal Structure of L-fuculose-1-phosphate aldolase from Bacteroides thetaiotaomicron · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9RQ12
- Elsewhere: RCSB PDB 2OPI · PDBe 2OPI · UniProt Q9RQ12
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.