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Crystal structure of the neisseria meningitidis minor type IV pilin, pilx, in space group P43

Analyse Crystal structure of the neisseria meningitidis minor type IV pilin, pilx, in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OPE
Type: protein
Length: 465 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pilx
Pockets: 1 · best druggability 0.78

Structure

x-ray diffraction · 3 distinct chains · 41% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Pilx	protein	120	40% helix, 25% strand	—
C	Pilx	protein	111	43% helix, 23% strand	—
D	Pilx	protein	114	41% helix, 23% strand	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1051	0.78	0.80	96	empty

Interfaces

5 interfaces between chains.

A–B · 505 Å² buried · 6 hydrogen bonds · protein-protein
A–D · 501 Å² buried · 7 hydrogen bonds · protein-protein
B–C · 482 Å² buried · 5 hydrogen bonds · protein-protein
B–D · 196 Å² buried · 1 hydrogen bond · protein-protein
A–C · 192 Å² buried · 0 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

2OPE · Crystal structure of the Neisseria meningitidis minor Type IV pilin, PilX, in space group… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2OPE · PDBe 2OPE

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