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Crystal structure of protein AF2318 from archaeglobus fulgidus, pfam DUF54

Analyse Crystal structure of protein AF2318 from archaeglobus fulgidus, pfam DUF54 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2OGK
Type
protein
Length
545 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Hypothetical protein
UniProt
O27966
Pockets
2 · best druggability 0.79

Structure

x-ray diffraction · 4 distinct chains · 38% helix, 29% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHypothetical proteinprotein13342% helix, 28% strandO27966
BHypothetical proteinprotein13934% helix, 29% strandO27966
CHypothetical proteinprotein13140% helix, 27% strandO27966
DHypothetical proteinprotein14237% helix, 32% strandO27966

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
110240.790.8188empty
23420.600.7843empty

Interfaces

4 interfaces between chains.

  • B–D · 682 Ų buried · 17 hydrogen bonds · protein-protein
  • C–D · 564 Ų buried · 12 hydrogen bonds · protein-protein
  • A–D · 308 Ų buried · 3 hydrogen bonds · protein-protein
  • A–B · 26 Ų buried · 0 hydrogen bonds · protein-protein

Compared structures

  • 2OGK · Crystal structure of protein AF2318 from Archaeglobus fulgidus, Pfam DUF54 · the same entry in another collection · chain A against A, TM-score 1.00

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