GL1X · GenesisL1 explorer

Research workbench

Protein of unknown function (DUF1342) from vibrio parahaemolyticus

Analyse Protein of unknown function (DUF1342) from vibrio parahaemolyticus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2OEZ
Type
protein
Length
484 residues
Chains
2
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
UPF0289 protein VP2528
UniProt
Q87LT3
Pockets
8 · best druggability 0.68

Structure

x-ray diffraction · 2 distinct chains · 54% helix, 20% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AUPF0289 protein VP2528protein24155% helix, 20% strandQ87LT3
BUPF0289 protein VP2528protein24353% helix, 20% strandQ87LT3

Pockets

8 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13730.680.8131empty
23280.610.7833empty
33500.610.7826empty
4670.430.8117empty
51200.420.7617empty

Interfaces

1 interface between chains.

  • A–B · 1964 Ų buried · 12 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

  • 2OEZ · Protein of Unknown Function (DUF1342) from Vibrio parahaemolyticus · the same entry in another collection · chain A against A, TM-score 1.00
  • Q87LT3 · AlphaFold monomer V2.0 prediction for cell division protein zapd (Q87LT3) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.