Research workbench
Structure of ALIX/AIP1 V domain
Analyse Structure of ALIX/AIP1 V domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2OEX
- Type
- protein
- Length
- 683 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Programmed cell death 6-interacting protein
- UniProt
- Q8WUM4
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 83% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Programmed cell death 6-interacting protein | protein | 342 | 85% helix, 0% strand | Q8WUM4 |
| B | Programmed cell death 6-interacting protein | protein | 341 | 81% helix, 0% strand | Q8WUM4 |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 90 | 0.73 | 0.95 | 21 | empty |
| 2 | 772 | 0.68 | 0.75 | 61 | empty |
| 3 | 111 | 0.66 | 0.90 | 25 | empty |
| 4 | 284 | 0.54 | 0.76 | 36 | empty |
| 5 | 71 | 0.28 | 0.73 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 230 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8WUM4
- Elsewhere: RCSB PDB 2OEX · PDBe 2OEX · UniProt Q8WUM4
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.