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Probable transcriptional regulator from pseudomonas aeruginosa

Analyse Probable transcriptional regulator from pseudomonas aeruginosa in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2OER
Type: protein
Length: 368 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable transcriptional regulator
UniProt: Q9I3U1
Pockets: 4 · best druggability 0.71

Structure

x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable transcriptional regulator	protein	179	81% helix, 0% strand	Q9I3U1
B	Probable transcriptional regulator	protein	189	79% helix, 0% strand	Q9I3U1

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	492	0.71	0.81	52	empty
2	284	0.69	0.84	47	empty
3	119	0.39	0.74	25	empty
4	97	0.34	0.73	19	empty

Interfaces

1 interface between chains.

A–B · 1037 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

2OER · Probable Transcriptional Regulator from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I3U1
Elsewhere: RCSB PDB 2OER · PDBe 2OER · UniProt Q9I3U1

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